Research 2018-02-02T17:02:35-08:00

To see a list of all articles published on PubMed about tongue-tie or ankyloglossia press here.


Randomized controlled trials of tongue-tie or ankyloglossia

  1. Hogan M, Westcott C, Griffiths M. Randomized, controlled trial of division of tongue-tie in infants with feeding problems. J Paediatr Child Health. 2005;41:246-50.

  2. Dollberg S, Botzer E, Grunis E, Mimouni FB. Immediate nipple pain relief after frenotomy in breast-fed infants with ankyloglossia: a randomized, prospective study. J Pediatr Surg. 2006;41:1598-600.

  3. Buryk M, Bloom D, Shope T. Efficacy of neonatal release of ankyloglossia: a randomized trial. Pediatrics. 2011;128:280-8. (Free full text)

  4. Berry J, Griffiths M, Westcott C. A double-blind, randomized, controlled trial of tongue-tie division and its immediate effect on breastfeeding. Breastfeed Med. 2012;7:189-93.

  5. Emond A, Ingram J, Johnson D, Blair P, Whitelaw A, Copeland M, Sutcliffe A. Randomised controlled trial of early frenotomy in breastfed infants with mild-moderate tongue-tie. Arch Dis Child Fetal Neonatal Ed. 2014;99:F189-95. (Free full text.)

  6. Ovental A, Marom R, Botzer E, Batscha N, Dollberg S. Using topical benzocaine before lingual frenotomy did not reduce crying and should be discouraged. Acta Paediatr. 2014;103:780-2.


Systematic Reviews

  1. Francis DO, Chinnadurai S, Morad A, Epstein RA, Kohanim S, Krishnaswami S, Sathe NA, McPheeters ML.Treatments for Ankyloglossia and Ankyloglossia With Concomitant Lip-Tie [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2015 May. (Free full text)

  2. Chinnadurai S, Francis DO, Epstein RA, Morad A, Kohanim S, McPheeters M. Treatment of ankyloglossia for reasons other than breastfeeding: a systematic review. Pediatrics. 2015;135:e1467-74.

  3. Francis DO, Krishnaswami S, McPheeters M. Treatment of ankyloglossia and breastfeeding outcomes: a systematic review. Pediatrics. 2015 Jun;135(6):e1458-66.

  4. Ito Y. Does frenotomy improve breast-feeding difficulties in infants with ankyloglossia? . Pediatr Int. 2014;56:497-505.

  5. Webb AN, Hao W, Hong P. The effect of tongue-tie division on breastfeeding and speech articulation: a systematic review. Int J Pediatr Otorhinolaryngol. 2013 May;77(5):635-46.

  6. Suter VG, Bornstein MM. Ankyloglossia: facts and myths in diagnosis and treatment. J Periodontol. 2009 Aug;80(8):1204-19.

  7. Segal LM, Stephenson R, Dawes M, Feldman P. Prevalence, diagnosis, and treatment of ankyloglossia: methodologic review. Can Fam Physician. 2007 Jun;53(6):1027-33. (Free Full Text)


Follow-up studies

  1. Dollberg S, Marom R, Botzer E. Lingual frenotomy for breastfeeding difficulties: a prospective followup study. Breastfeed Med. 2014;9:286-9.

  2. Griffiths DM. Do tongue ties affect breastfeeding? J Hum Lact. 2004;20:409-14



Frenotomy for Speech dysfunction

  1. Ito Y, Shimizu T, Nakamura T, Takatama C. Effectiveness of tongue-tie division for speech disorder in children. Pediatr Int. 2015;57:222-6.

  2. Walls A, Pierce M, Wang H, Steehler A, Steehler M, Harley EH Jr. Parental perception of speech and tongue mobility in three-year olds after neonatal frenotomy. Int J Pediatr Otorhinolaryngol. 2014;78:128-31.

  3. Webb AN, Hao W, Hong P. The effect of tongue-tie division on breastfeeding and speech articulation: a systematic review. Int J Pediatr Otorhinolaryngol. 2013;77:635-46.

  4. Dollberg S, Manor Y, Makai E, Botzer E. Evaluation of speech intelligibility in children with tongue-tie. Acta Paediatr. 2011;100:e125-7

  5. Messner AH, Lalakea ML The effect of ankyloglossia on speech in children. Otolaryngol Head Neck Surg. 2002;127:539-45.

  6. Block JR. The role of the speech clinician in determining indications for frenulotomy in cases ofankyloglossia. N Y State Dent J. 1968;34:479-81.

Ankyloglossia and airway anatomy

  1. Mukai S, Mukai C, Asaoka K Congenital ankyloglossia with deviation of the epiglottis and larynx: symptoms and respiratory function in adults. Ann Otol Rhinol Laryngol. 1993;102:620-4.

  2. Mukai S, Mukai C, Asaoka K. Ankyloglossia with deviation of the epiglottis and larynx. Ann Otol Rhinol Laryngol Suppl. 1991 May;153:3-20